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Vidalista 40 mg can be taken with or without food. However, high-fat meals may delay its onset of action, so it's advisable to avoid them close to the time of taking the medication. Vidalista 40 mg is a medication prescribed for the treatment of erectile dysfunction (ED). It contains tadalafil, the same active ingredient found in Cialis. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor, which helps improve erectile function by enhancing blood flow to the penis.