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Tadarise 40 mg is a prescription medicine used to treat erectile dysfunction (ED) in men. It contains Tadalafil, which works by improving blood flow to the penis during sexual stimulation. Tadalafil blocks the PDE5 enzyme, increasing levels of cGMP. This relaxes smooth muscles in penile blood vessels, allowing more blood to flow into the penis when a man is sexually aroused. It does not cause an erection on its own—sexual stimulation is required.