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Poxet 90 mg should not be combined with MAO inhibitors and may also interact with other antidepressants, thioridazine, tramadol, migraine medicines, warfarin, and alcohol. It should be used cautiously in people with heart disease, liver or kidney problems, epilepsy, glaucoma, or a history of fainting. If dizziness or sleepiness occurs, driving and heavy machinery should be avoided until the effect is known. Common side effects include headache, dizziness, nausea, vomiting, indigestion, fatigue, dry mouth, drowsiness, and sweating. Some people may also experience restlessness, insomnia, or blurred vision. Rare but serious effects can include fainting, seizures, mood changes, or serotonin syndrome, especially if taken with incompatible medicines.