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For the treatment of moderate to severe pain, synthetic opioid analgesics like tramadol are employed. It is frequently administered for long-term ailments like arthritis or to treat pain following surgery. Tramadol is offered under a number of different brand names.
By attaching itself to the brain's and spinal cord's mu-opioid receptors, tramadol modifies how the body experiences and reacts to pain. Tramadol also inhibits the reuptake of norepinephrine and serotonin, which may be a factor in its analgesic effects.
In contrast to certain other opioids, tramadol is thought to carry a lower risk of abuse and dependence. But it still has the potential to become addictive, so use needs to be carefully controlled.