Most likely possible through GATT client
https://docs.micropython.org/en/latest/library/ubluetooth.html#gatt-client

from m5stack import *
from m5ui import *
from uiflow import *
import time
import uos

setScreenColor(0x000000)

vstart = None
vsysinfo = None
vsecs = None
vmins = None
vtimetext = None

battery = M5TextBox(0, 0, "loading", lcd.FONT_DejaVu18, 0xFFFFFF, rotate=0)
uptime = M5TextBox(0, 32, "loading", lcd.FONT_DejaVu18, 0xFFFFFF, rotate=0)
lb_sysinfo = M5TextBox(0, 64, "loading", lcd.FONT_DejaVu18, 0xFFFFFF, rotate=0)

import math

lcd.setBrightness(10)
vstart = time.ticks_ms()
vsysinfo = uos.uname()
lb_sysinfo.setText(str(vsysinfo))
while True:
  battery.setText(str((str(((str('Battery: ') + str((power.getBatteryLevel()))))) + str('%'))))
  vsecs = round(((time.ticks_ms()) - vstart) / 1000)
  vmins = math.floor(vsecs / 60)
  vtimetext = (str((vsecs % 60)) + str('s'))
  if vmins != 0:
    vtimetext = (str(((str(vmins) + str('m ')))) + str(vtimetext))
  vtimetext = (str('Uptime: ') + str(vtimetext))
  uptime.setText(str(vtimetext))
  wait_ms(2)

My first time working with this hardware and UIflow / uPython I made a super simple RGB mixer.

(ty felmue for teaching me how to format code)

from m5stack import 
from m5ui import 
from uiflow import 

setScreenColor(0x222222)

varBarFactor = None
varR = None
varG = None
varB = None
varHexR = None
varHexG = None
varHexB = None

lb_RGBval = M5TextBox(26, 8, RGB, lcd.FONT_UNICODE, 0xFFFFFF, rotate=90)
rec_R = M5Rect(44, 240, 50, 0, 0xff0000, 0xff0000)
rec_G = M5Rect(133, 240, 50, 0, 0x00ff00, 0x00ff00)
rec_B = M5Rect(224, 240, 50, 0, 0x0000ff, 0x0000ff)

def workR()
  global varBarFactor, varR, varG, varB, varHexR, varHexG, varHexB
  if btnA.isPressed()
    varR = varR + 1
    if varR  255
      varR = 0
    rec_R.setSize(height=int((varR  varBarFactor)))
    rec_R.setPosition(y=(240 - int((varR  varBarFactor))))
    varHexR = str(hex(varR))[2]
    if len(varHexR)  2
      varHexR = (str('0') + str(varHexR))

def workG()
  global varBarFactor, varR, varG, varB, varHexR, varHexG, varHexB
  if btnB.isPressed()
    varG = varG + 1
    if varG  255
      varG = 0
    rec_G.setSize(height=int((varG  varBarFactor)))
    rec_G.setPosition(y=(240 - int((varG  varBarFactor))))
    varHexG = str(hex(varG))[2]
    if len(varHexG)  2
      varHexG = (str('0') + str(varHexG))

def workB()
  global varBarFactor, varR, varG, varB, varHexR, varHexG, varHexB
  if btnC.isPressed()
    varB = varB + 1
    if varB  255
      varB = 0
    rec_B.setSize(height=int((varB  varBarFactor)))
    rec_B.setPosition(y=(240 - int((varB  varBarFactor))))
    varHexB = str(hex(varB))[2]
    if len(varHexB)  2
      varHexB = (str('0') + str(varHexB))

lcd.setBrightness(10)
varBarFactor = 0.95
varHexR = '00'
varHexG = '00'
varHexB = '00'
varR = 0
varG = 0
varB = 0
while True
  workR()
  workG()
  workB()
  rgb.setColorAll((varR  16)  (varG  8)  varB)
  lb_RGBval.setText(str((str('RGB #') + str(((str(varHexR) + str(((str(varHexG) + str(varHexB))))))))))
  wait_ms(2)

I need my Core to write a characteristic to a BLE device (lightbulb) like so:
http://slides.com/helenst/ble#/0/17

How can I do that in UIflow or Micropython?

Great job. Does this work the same with the old (blue) LoRaWAN module?

I want to use the LoRaWAN module with the Fire Core.
I am confused about the necessary hardware modifications. It says:

• M5Stack Fire has occupied GPIO16 / 17 to connect with the PSRAM by default, it's conflict with TXD / RXD (GPIO16, GPIO17) in this module. Therefore, when using the LoRaWAN module with the M5Stack Fire, you might have to cut the TXD and RXD from GPS module and wire fly to another set of UART pin, if you gonna use the PSRAM.

Why does it talk about a GPS module? What connections am I meant to cut? Could someone please clarify?